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KMID : 0361020220650050253
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Korean Journal of Otolaryngology - Head and Neck Surgery
2022 Volume.65 No. 5 p.253 ~ p.259
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Role and Recent Trend of Intraoperative Parathyroid Hormone Monitoring During Parathyroidectomy in Patients With Primary Hyperparathyroidism
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Ahn Dong-Bin
Kwak Ji-Hye
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Abstract
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In the last few decades, the standard surgical treatment for primary hyperparathyroidism (PHPT) has shifted from bilateral neck exploration to focused/minimally invasive parathy- roidectomy (FMIP). This shift was accelerated by the introduction of intraoperative parathy- roid hormone (IOPTH) monitoring, which can provide intraoperative information regarding the localization and complete excision of the pathological parathyroid gland during FMIP. Since the first clinical application of the IOPTH assay in 1991, IOPTH monitoring has sub- stantially improved to date to increase its performance and availability. In addition, the clini- cal applications of IOPTH changed with the needs of actual clinical practice, although the fundamental concept and technique remained unchanged. In this review, we discuss the role of IOPTH monitoring in the surgical management of PHPT based on the results of contempo- rary studies and summarized the major issues regarding IOPTH.
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KEYWORD
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Monitoring, intraoperative, Parathyroid hormone, Parathyroidectomy
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